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Panama Canal

California Cruise Guide > Cruises > Panama Canal

Panama Canal Cruises from California

Cruise from California through the Panama Canal, one of the man-made wonders of the world. The canal is 100 years old but is still an awe inspiring engineering feat, and the best way to experience it is on a cruise.

Panama Canal cruises depart from Los Angeles, San Diego or San Francisco. They finish in Miami, Fort Lauderdale, Tampa or New York.

On your journey you'll visit tropical ports in countries like Mexico, Costa Rica and Colombia.

2021

15-day Panama Canal cruise on Norwegian. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Cartagena (Colombia) and Great Stirrup Cay (Bahamas).
• 2021 departure: October 6.

15-night Panama Canal cruise on Celebrity. One-way from San Diego to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Colon (Panama) and Cartagena (Colombia).
• 2021 departure: October 27.

17-day Panama Canal cruise on Norwegian. One-way from San Francisco to Miami (Florida). Visit San Diego (California), Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Panama City (Panama) and Cartagena (Colombia).
• 2021 departure: October 28.

14-night Panama Canal cruise on Disney. One-way from San Diego to Galveston (Texas). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), the Panama Canal, Cartagena (Colombia), Grand Cayman (Cayman Islands) and Cozumel (Mexico).
• 2021 departure: November 5.

2022

14-day Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2022 departure: January 2.

11-day Panama Canal cruise on Norwegian. One-way from San Diego to Panama City (Panama). Visit Cabo San Lucas (Mexico), Puerto Quetzal (Guatemala), Acajutla (El Salvador), San Juan del Sur (Nicaragua) and Puntarenas (Costa Rica).
• 2022 departure: January 9.

14-day Panama Canal cruise on Norwegian. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Panama City (Panama) and Cartagena (Colombia).
• 2022 departure: January 21.

15-day Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2022 departure: January 28.

14-day Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Panama Canal and Cartagena (Colombia).
• 2022 departure: January 30.

15-day Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2022 departure: February 12.

15-day Panama Canal cruise on Princess. One-way from San Francisco to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2022 departure: February 25.

15-day Panama Canal cruise on Princess. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Cartagena (Colombia).
• 2022 departure: May 11.

14-night Panama Canal cruise on Cunard. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puntarenas (Costa Rica), the Panama Canal and Oranjsestad (Aruba).
• 2022 departure: July 26.

18-night Panama Canal cruise on Crystal. One-way from Los Angeles to New York. Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia), Key West (Florida) and Charleston (South Carolina).
• 2022 departure: August 15.

13-day Panama Canal cruise on Royal Caribbean. One-way from Los Angeles to Tampa (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Huatulco (Mexico), Puntarenas (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2022 departure: October 2.

17-day Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Panama Canal, Aruba and Half Moon Cay (Bahamas).
• 2022 departure: October 8.

16-day Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Panama Canal and Aruba.
• 2022 departure: October 13.

12-day Panama Canal cruise on Norwegian. One-way from Los Angeles to Panama City (Panama). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua) and Puntarenas (Costa Rica).
• 2022 departure: November 12.

14-day Panama Canal cruise on Holland America. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Panama Canal and Cartagena (Colombia).
• 2022 departure: November 17.

15-day Panama Canal cruise on Norwegian. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2022 departure: December 2.

15-night Panama Canal cruise on Celebrity. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Colon (Panama) and Cartagena (Colombia).
• 2022 departure: December 19.

2023

16-night Panama Canal cruise on Regent Seven Seas. One-way from Los Angeles to Miami (Florida). Visit Catalina Island (California), Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2023 departure: January 5.

Panama Canal cruise from California
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