Holland America Line offers cruises from San Diego in California. They specialize in long cruises to exotic destinations. The selection includes Coastal, Hawaii and Christmas cruises. See the details below.
Holland America's mid-size luxury ships feature attentive service, fine dining and interesting activities. Amenities include valuable art collections, Dancing with the Stars: At Sea, the Culinary Arts Center, Greenhouse Spa, live entertainment, and multiple restaurants to explore.
7-day Pacific Coastal cruise on Koningsdam. One-way from San Diego to Vancouver (Canada). Visit Catalina Island (California), San Francisco (California), Astoria (Oregon) and Victoria (Canada).
• 2025 departure: March 29.
7-day California Coast cruise on Zaandam. Round-trip from San Diego to Ensenada (Mexico), San Francisco (California) and Santa Barbara (California).
• 2025 departure: April 19.
6-day Pacific Coastal cruise on Eurodam. One-way from San Diego to Vancouver (Canada). Visit Catalina Island (California) and San Francisco (California).
• 2025 departure: April 26.
4-day Pacific Coastal cruise on Nieuw Amsterdam. One-way from San Diego to Vancouver (Canada). Visit Catalina Island (California).
• 2025 departure: April 30.
4-day Pacific Coastal cruise on Zaandam. One-way from San Diego to Vancouver (Canada). Visit Catalina Island (California).
• 2025 departure: May 3.
7-day California Coast cruise on Nieuw Amsterdam. Round-trip from San Diego to Ensenada (Mexico), San Francisco (California) and Santa Barbara (California).
• 2025 departure: October 11.
4-day California Coast cruise on Koningsdam. Round-trip from San Diego to Santa Barbara (California), Catalina Island (California) and Ensenada (Mexico).
• 2025 departure: October 21.
7-day California Coast cruise on Nieuw Amsterdam. Round-trip from San Diego to Catalina Island (California), San Francisco (California) and Ensenada (Mexico).
• 2025 departure: November 1.
17-day cruise to Hawaii on the Koningsdam. Round-trip from San Diego to Honolulu (Hawaii), Kauai (Hawaii), Maui (Hawaii), Hilo (Hawaii), Kona (Hawaii) and Ensenada (Mexico).
• 2025 departure: January 11.
18-day cruise to Hawaii on the Koningsdam. Round-trip from San Diego to Honolulu (Hawaii), Kauai (Hawaii), Maui (Hawaii), Kona (Hawaii), Hilo (Hawaii) and Ensenada (Mexico).
• 2025 departure: January 28.
35-day cruise to Hawaii & the South Pacific on the Koningsdam. Round-trip from San Diego to Kona (Hawaii), Maui (Hawaii), Honolulu (Hawaii), Kauai (Hawaii), Fanning Island, Raiatea, Tahiti, Moorea, Fakarava and Nuku Hiva.
• 2025 departure: February 15.
51-day cruise to Hawaii & the South Pacific on the Zaandam. Round-trip from San Diego to Santa Barbara (California), Kona (Hawaii), Kauai (Hawaii), Honolulu (Hawaii), Maui (Hawaii), Hilo (Hawaii), Fanning Island (Kiribati), Pago Pago (American Samoa), Apia (Samoa), Suva (Fiji), Dravuni (Fiji), Lautoka (Fiji), Savusavu (Fiji), Nuku Alofa (Tonga), Vavau (Tonga), Aitutaki (Cook Islands), Rarotonga (Cook Islands), Raiatea (Society Islands), Moorea (French Polynesia), Huahine (French Polynesia), Tahiti (French Polynesia), Rangiroa (French Polynesia), Fakarava (French Polynesia) and Nuku Hiva (French Polynesia).
• 2025 departure: September 29.
17-day cruise to Hawaii on the Zaandam. Round-trip from San Diego to Kona (Hawaii), Honolulu (Hawaii), Maui (Hawaii), Hilo (Hawaii) and Ensenada (Mexico).
• 2025 departure: November 19.
17-day cruise to Hawaii on the Zaandam. Round-trip from San Diego to Hilo (Hawaii), Maui (Hawaii), Kona (Hawaii), Honolulu (Hawaii) and Ensenada (Mexico).
• 2025 departure: December 18.
7-day cruise to Mexico. Round-trip from San Diego to Cabo San Lucas (Mexico), La Paz (Mexico) and Loreto (Mexico).
• 2025 departures: January 4; April 12; October 25; November 15; December 20.
7-day cruise to Mexico. Round-trip from San Diego to Cabo San Lucas (Mexico), Mazatlan (Mexico) and Puerto Vallarta (Mexico).
• 2025 departures: March 22; April 26; October 18; November 8, 22; December 27.
7-day cruise to Mexico. Round-trip from San Diego to Ensenada (Mexico), Cabo San Lucas (Mexico) and Puerto Vallarta (Mexico).
• 2025 departure: October 4.
10-day cruise to Mexico. Round-trip from San Diego to Cabo San Lucas (Mexico), La Paz (Mexico), Loreto (Mexico), Mazatlan (Mexico) and Puerto Vallarta (Mexico).
• 2025 departures: April 2; November 29.
11-day cruise to Mexico. Round-trip from San Diego to Bahia Magdalena (Mexico), Cabo San Lucas (Mexico), La Paz (Mexico), Loreto (Mexico), Mazatlan (Mexico), Puerto Vallarta (Mexico) and Manzanillo (Mexico).
• 2025 departure: March 22.
11-day cruise to Mexico. Round-trip from San Diego to Puerto Vallarta (Mexico), Manzanillo (Mexico), Mazatlan (Mexico), Loreto (Mexico), La Paz (Mexico) and Cabo San Lucas (Mexico).
• 2025 departure: December 9.
12-day cruise to Mexico. Round-trip from San Diego to Cabo San Lucas (Mexico), La Paz (Mexico), Loreto (Mexico), Mazatlan (Mexico), Puerto Vallarta (Mexico), Manzanillo (Mexico) and Ensenada (Mexico).
• 2025 departure: December 6.
15-day Panama Canal cruise on the Zaandam. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), the Panama Canal, Cartagena (Colombia) and Half Moon Cay (Bahamas).
• 2025 departure: January 3.
17-day Panama Canal cruise on the Eurodam. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Acajutla (El Salvador), Puntarenas (Costa Rica), the Panama Canal and Aruba.
• 2025 departure: October 9.
17-day Panama Canal cruise on the Koningsdam. One-way from San Diego to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Oranjestad (Aruba) and Half Moon Cay (Bahamas).
• 2025 departure: November 1.
